The clinical case of an 11-year-old male patients presented, treated at the Internal Medicine Service of the Hospital Regional de Alta Especialidad del Niño Dr. Rodolfo Nieto Padrón, Tabasco for presenting weakness of the upper and lower extremities of 4 days of evolution at the time of admission, with the history that 17 days prior to the onset of weakness, he had fever and dysgeusia treated only with antipyretic. Complementary studies were carried out such as a lumbar puncture which was normal, as well as a Magnetic resonance of the spine with which the diagnosis of transverse myelitis is reached and as an etiological agent SARS-CoV-2 since it presented positive IgG antibodies and negative IgM these observed In blood serum, no treatment directed at SARS-CoV-2 was given, only treatment with pulses of steroid for myelitis, after which the Patient evolved satisfactorily.