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The Instituto Mexicano del Seguro Social (IMSS) is the institution with the greatest health coverage in Mexico. In adherence to existing and committed to provide specialized services to specific populations (vulnerable age groups, such as children and young people in primary, secondary and higher education, productive and without social security educational training), this gives the renal replacement therapy -peritoneal dialysis and hemodialysis- at no cost to students. Cross-sectional and retrospective study conducted from 1 to 30 September 2016; Census Patients with Chronical Renal Failure, sociodemographic and type of therapy are identified; direct costs are estimated. At 25 August 2016 to 16 426 was addressed to 26 years old, 279 male (65%) and 147 female (35%). The causes IRC were congenital problems 194 (45%), chronic glomerular diseases 111 (26%), diabetes mellitus type 1, 58 (14%), polycystic kidneys 7 (2%) and undetermined causes 56 (13%). 78 patients received CAPD, APD 208, 61 HD and 79 HD IM MS. The average annual investment per patient was 75 827.47 mexican pesos; the costs were in CAPD dialysis modality $ 41 931.20, DPA $ 64 123.20, HD intramural $ 33 301.32 and extramural $ 165 360.00; which generated a cash cost of $ 32 302 503.40 mexican pesos These data demonstrate the Institute commitment to society in granting health, preserve life and improve the quality of life of Mexicans and stage of health risk posed by the IRC.