Smoking is a global public health problem, which directly affects the health of the smokers and passively the people around them. The World Health Organization has recommended the implementation of control measures for its consumption, marketing and advertising. A quasi-experimental study was conducted on the implementation of an educational program based on the strategic lines of the Tobacco Smoke Free Space in 224 adults (124 users and 100 workers) of the Family Medical Unit, in addition to knowledge about tobacco through some questions of the Manual of smoke-free prior to and after educational intervention. The educational intervention was divided into 5 steps, in which the population was trained and guided about smoking, informing about the consequences, damage to health, treatments among other topics, in 60-minute sessions for groups of 3 to 5 attendees. Prior to the intervention, 16, 9% of users and 18% of workers were smokers, after this educational intervention the percentage was reduced to 14, 5% (p=0,250) and 16% (p=0,500) respectively without finding significant differences, however the implementation of the program improved the level of knowledge on the policy of the Tobacco Smoke-Free Space (p=0,008) (p=0,005), also helped adults identify the harmful effects of tobacco.