In this paper, we emphasize on a probable atypical case of Zika, which is essentially a febrile illness; however, nowadays it has been noticed that fever is not always present in Zika cases, and the incidence of this clinical sign varies in several series; besides, we point out that symptoms such as nonpurulent conjunctivitis or rash could be reliable criteria in the absence of fever for the probable diagnosis of Zika, which invariably requires serological confirmation, even though the latter is not always available.