To determine the cost of caring for the diabetic-hypertensive patient in primary care. A cost analysis carried out in family medicine units in Mexico. Family medicine units in Mexico. Patients with diabetes and hypertension. Include the profile of use of the services and the cost of the care. The profile is defined as the average annual use of primary care services, the unit cost is calculated by reason for use in each of the services used, taking the fixed and variable consumables into account; the average cost by reason for care is calculated from use-cost ratio and the mean annual cost from the total average cost by reason for the care. The mean annual cost in the family doctor clinic was euro180.65 (95% confidence interval [CI], 168.31-193), in the laboratory, euro48.99 (95% CI, 44.85-53.18), and in the rest of the primary care services, euro41.33 (95% CI, 30.19-52.46). The mean annual primary care cost per patient was euro271 (95% CI, 243.36- 298.65). The primary care costs of the diabetic-hypertensive patient are concentrated in the family doctor and laboratory services.