Diabetes type 2 has increased in adult women due to higher frequency of obesity and sedentary lifestyle, and thus cardiovascular diseases have increased. Hyperglycemia control and, collaterally, high blood pressure and dyslipidemia correction are the basis of its therapy. This paper evaluates oral antidiabetic drugs effectiveness and preference. Gestational diabetes is a cause of morbidity and mortality in fetuses and newborns, it has to be timely diagnosed, and needs a strict control, same to diabetes type 1. Gyneco-obstetrical doctor must be alert to diabetes signs and closely work in its therapy. Key words: type 2 diabetes mellitus, diabetes in adult women, gestational diabetes, oral antidiabetic drugs, insulin therapy, hypertension, dyslipoproteinemia, cardiovascular disease.