Ethnographic, nutrition and genetic differences are known that determine diverse clinical outcomes all over the world and to enhanced according to geographic location. In the State of Michoacan, Mexico, the 50.7% of the population lives a rural lifestyle and the 20% are women in reproductive age with a birth rate of 37.8 x 1000 inhabitants per year, which is significant to asses weight gain behavior during pregnancy. The objective of this study was to evaluate the Gestational Weight Gain Pattern (GWGP) in the east rural area in the State of Michoacan, and comparing this with women in the urban area of Morelia city. The research was performed during six months, in which 68 women with normal pregnancy were enrolled and controlled throughout their pregnancy in the rural clinics and who received attention for labor and delivery in a hospital. The inclusion criteria was: a first consultation before the 14 weeks of gestation. Pregnancy and delivery attention was granted according with the Mexican Official Norm (Norma Official Mexicana). The results indicated that the pregnancy weight gain assessed every three months and globally were significantly different in both populations in the second and third trimesters except in the first trimester, and it was significantly higher for the urban population, p > .05. The women age at the pregnancy, the school education, the number of prenatal consultations were less in the native women, the parity was significantly higher in the rural area, p > .05. There were no differences in the Body Mass Index (BMI).